Targeting Mechanisms of Aging Cross Species
Ira Pastor, ideaXme life sciences ambassador and founder of Bioquark, interviews Dr. Matt Kaeberlein, Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington.
Dr. Matt Kaeberlein’s Research: Targeting Mechanisms of Cross Species Aging
Dr. Matt Kaeberlein, is Professor of Pathology, Adjunct Professor of Genome Sciences, and Adjunct Professor of Oral Health Sciences at the University of Washington. With a PhD from MIT in Biology, and post-doctoral work in the Department of Genome Sciences, University of Washington, his research interests are focused on basic mechanisms of aging in order to facilitate translational interventions that promote healthspan and improve quality of life.
Dr. Kaeberlein has published nearly 200 papers in top scientific journals and has been recognized by several prestigious awards, including a Breakthroughs in Gerontology Award, an Alzheimer’s Association Young Investigator Award, an Ellison Medical Foundation New Scholar in Aging Award, a Murdock Trust Award, a Pioneer in Aging Award, and the Vincent Cristofalo Rising Star in Aging Research.
Dr. Kaeberlein’s contributions have also been recognized with Fellow status in the American Association for the Advancement of Science, the American Aging Association, and the Gerontological Society of America.
Dr. Kaeberlein is a past President of the American Aging Association and has served on their Executive Committee and Board of Directors since 2012. He has also served as a member of the Board of Directors for the Federation of American Societies for Experimental Biology and is currently the Chair of the Biological Sciences Section of the Gerontological Society of America.
Dr. Kaeberlein serves on the editorial boards for several journals, including Science and eLife. Dr. Kaeberlein’s scientific discoveries have generated substantial public interest, with featured stories in major media outlets including appearing on the front page of the New York Times, the Today Show, CNN, the UK Telegraph, Popular Science, Time Magazine, Scientific American, NPR, USA Today, National Geographic, and many others. In addition to his primary appointments, Dr. Kaeberlein is the co-Director of the University of Washington Nathan Shock Center of Excellence in the Basic Biology of Aging, the founding Director of the Healthy Aging and Longevity Research Institute at the University of Washington, and founder and co-Director of the Dog Aging Project.
On this episode we will hear from Dr. Kaeberlein about:
His background and how he developed an interest in genomics, in biology, and in aging. His strategy in studying the “conserved” mechanisms of aging across organisms including yeast, nematodes, mice, and dogs. His studies with the drug Rapamycin in rejuvenating oral health in aging mice. His studies on the purification and analysis of nematode extracellular vesicles and their roles in studying the bio-markers of health and disease. His studies on systems biology in yeast to help illuminate mechanisms of personalized aging. His dog aging studies where he will be studying up to 10,000 dogs, in a 10-year effort aimed at tracking their health and identifying factors that can lengthen their lifespan.
This interview is in American English
Credits: Ira Pastor interview video, text, and audio.
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If you liked this interview, be sure to read this interview with Dr. Mark Wolff!
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